Q&A Residential Hotel offers really nice apartments for short term stays. We stayed for 6 nights and were very happy with our choice. The hotel is located in a street parallel to Wall St, close to several subway stations. Dining and grocery options are close by.
The location is perfect as a starting point for exploring Manhattan and the rest of the city. Compared to many other hotels, the apartments are spacious and have a fully equipped kitchen.
The only slightly negative point was the noise level. Our apartment was on the 3rd floor with window to the street, directly opposite to an AC outlet of the building across. Also, the AC in the room was located directly behind the headrest of the bed, which might be a bit problematic if your sleep is sensitive to noise.